Recognising the skin microbiome’s role in repairing damaged skin

An insect bite, a superficial scratch or cut, skin peeling or maybe a tattoo, our skin can be weakened in any number of ways, voluntary or involuntary. Recent scientific studies have demonstrated that the skin microbiome is key to the natural healing process. The microbiome helps to prevent infection and inflammation, and supports skin reconstruction.

Cleansing weakened skin no more than necessary

While it has become second nature to cleanse weakened skin to prevent any kind of infection, it has now also become clear that the use of antimicrobial agents more than necessary can actually slow the healing process. Applying topical antibacterial products removes the bad bacteria, but it also removes the good bacteria in our microbiota. Ensuring the use of a gentle, pH-balanced cleanser that respects the skin can help to prevent damaging the healthy microbiome diversity of the skin.

Man using Cicabio balm to heal a scar

Skin microbiome diversity and restoring skin health

The more healthy and diverse the skin’s microbiome, the more significantly it contributes to helping restore the epidermis. Acting on the skin’s surface, the microbiome helps to reduce colonisation and infection by pathogenic bacteria, calm inflammation and regrow tissue. It’s therefore essential to support the microbiome so that it can play its part during the natural healing process.

Cicabio Creme+, an ultra-repairing cream for the face, body and intimate areas in 40 ml

As a result of this new knowledge about the skin microbiome, BIODERMA has reinvented its iconic Cicabio Crème to become Cicabio Crème+. A new approach, a new formula and a new texture. 

Developed from the study of the skin's ecosystem and natural biology, it considers how the skin interacts with its environment and respects its own natural mechanisms to care for itself. Cicabio Crème+ helps to strengthen these mechanisms using biomimetic ingredients that restore microbiome diversity, help to optimise the natural healing process, and soothe itching sensations and discomfort. Cicabio Crème+ is the new go-to, multi-use product for anytime the skin become damaged, weakened or irritated.

The natural repair process

There are four overlapping stages involved in skin healing: stopping blood flow, calming inflammation, reconstructing tissue and reaching maturity. Each stage relies on a healthy skin microbiome and the skin being able to carry out its healing mechanisms. However, factors such as age, lifestyle and environment can slow some or all of these stages. Cicabio Crème+ has been formulated to nourish the microbiome and support the skin's natural healing process.

 

The microorganisms that live on skin feed on elements such as the sebum we produce and have adapted to skin’s slightly acidic environment. Cicabio Crème+’s formula respects and supports this ecosystem, helping to recreate favourable conditions where the skin’s microbiota can flourish. Cicabio Crème+ contains skin-identical biomimetic lipids that include squalene, which is found in sebum, and it has a pH the same as skin’s. Recognising the ingredients as part of its own composition, the skin absorbs them into its natural mechanisms and boosts microbiome restoration.

 

  • Support the healing process: 

Hydrated skin is better able to rebuild tissues and structures. BIODERMA's new and patented Optimal repair complex** has three skin-identical biomimetic ingredients with complementary actions. Polyglutamic acid retains 3,000 times its weight in water, keeping the skin’s surface moisturised and providing a breathable film. Hyaluronic acid penetrates deeper into the epidermis, while xylose is a restructuring agent that helps boost collagen production, making skin strong. A clinical study has measured an 88% increase in skin repair after seven days1, thanks to the Optimal Repair Complex.

**Patent application filed in France. 
1In vitro study on reconstructed skin model, epidermal closure at D7 after topical application of Optimal repair complex vs. untreated

Soothing itching sensations and discomfort

Skin that is healing can feel uncomfortable and often gets itchy. While this is normal, rubbing or scratching can interrupt the repair process, and only serves to prolong it. BIODERMA's Antalgicine™ biomimetic technology is inspired by a molecule naturally present in the body whose role is to soothe unpleasant sensations. Antalgicine™ therefore soothes these sensations of discomfort and itching. Healing has fewer interruptions, and quality of life during the healing process is restored.

AN ADAPTED SENSORIAL TEXTURE

In an easy-to-spread and pleasant, non-sticky and non-greasy texture, Cicabio Crème+ forms a breathable and protective film on skin. Acting almost like a shielding bandage, it aids the skin’s healing mechanisms as soon as you apply it.

Full-body tolerance and effectiveness, for all weakened skin

Skin can be weakened for any number of reasons, including superficial cuts and scratches, cosmetic procedures, nappy rash, getting a tattoo, and more. For use anywhere on the face, body, scalp and external intimate areas, Cicabio Crème+ is perfectly adapted to the needs of the whole family.

Clinically proven to restore skin health and minimise marks


Tested under dermatological, paediatric, gynaecological and ophthalmological supervision, Cicabio Crème+ has been clinically proven to restore the microbiome and help skin repair itself in the right conditions. 

  • 3 hours Cicabio Crème+ restores the skin’s microbiome 3 hours after application1
  • 88% drop in itching and sensations of discomfort2
  • 46% red marks lessened by 46%2
  • 32% drop in thickness2
  • 45% increase in skin’s suppleness*2

 

1Clinical study after disinfection, restoration of Shannon index (diversity and relative abundance of bacteria) 3 hours post-application of Cicabio Crème+ vs untreated disinfected zone, on 20 subjects
2Clinical study of Cicabio Crème+ on remodeling scars (C-section, eipisiotomy, adhesions) on 34 subjects, scoring at D14 vs D0
*Evaluation of the pliability of the skin

Cicabio Crème+

(No reviews yet)

A microbiome-centric approach to restoring all types of damaged and weakened skin. Optimise the skin's natural healing process.

Weakened, irritated skin